Preview

Рецепт

Расширенный поиск

СилваДепрекс: фармакологические особенности фитокомпозициидля поддержания нормального функционального состояния нервной системы

Полный текст:

Аннотация

СилваДепрекс - комбинированный растительный препарат. В его состав входят экстракты 6 видов растений: зверобоя продырявленного, родиолы розовой, валерианы лекарственной, володушки серповидной, муира пуама, красного клевера. Препарат повышает стрессоустойчивость, улучшает когнитивные функции, корригирует эмоциональный фон, что снижает тревожность, устраняет беспокойство и нормализует сон. Антидепрессивное действие препарата СилваДепрекс подтверждено результатами клинического исследования. При этом он мало- токсичен и противопоказан лишь при индивидуальной непереносимости компонентов препарата, беременности и грудном вскармливании. Достоинством препарата является и то, что, в отличие от большинства рецептурных нейротропных лекарственных средств, СилваДепрекс не влияет на способность к управлению транспортными средствами.

Об авторах

В. П. Вдовиченко
Гродненский государственный медицинский университет
Беларусь


В. В. Гончарук
Гродненский государственный медицинский университет
Беларусь


О. А. Борисенок
Гродненский государственный медицинский университет
Беларусь


Список литературы

1. Srole L. et al. (1962) Mental health in Metropolis, the Midtown Manhattan Study, vol. I.

2. Emeliantseva T.A. (2006) Nevrozogenez (multimodalnyy podkhod): metod. rekomendatsii [Neurogenesis (multimodal approach): method. recommendations]. Minsk: BGMU. (in Russian).

3. Shilova O.V., Khmara N.V. (2007) Osnovy obshchey i chastnoy psikhiatrii i narkologii: ucheb.-metod. posobiye k prakticheskim zanyatiyam po psikhiatrii i narkologii dlya studentov lechebnogo fakulteta [Elements of general and partial psychiatry and narcology: educ.-method. materials for practical classes in psychiatry and narcology for students of the Faculty of General Medicine]. Gomel: UO «GomGMU». (in Russian).

4. Krapivkin A.I. (2009) Ratsionalnaya fitoterapiya nevroticheskikh rasstroystv u detey [Rational phytotherapy of neurotic disorders in children]. Praktika pediatra, vol. 5, pp. 33-36.

5. Syropyatov O.G., Dzeruzhinskaya N.A. (2017) Fitoterapiya psikhosomaticheskikh rasstroystv [Phytotherapy of psychosomatic disorders]. Moskva: Litres. (in Russian).

6. Turishchev S.N. (2005) Fitoterapiya dlya vsekh [Phytotherapy for all]. Moskva: Olma-Press Invest. (in Russian).

7. Smulevich A.B. (2001) Depressii v obshchey meditsine. Rukovodstvo dlya vrachey [Depression in general medicine. A guide for doctors]. Moskva: Meditsinskoye informatsionnoye agentstvo. (in Russian).

8. SilvaDepreks - biologicheski-aktivnay dobavka k pishche [SilvaDepreks, a biologically active food additive]. Certificate of state registration No. KZ. 16.01.78.003.Е.004384.04.15 of 04/07/2015.

9. Pūce S. (2016) Otsenka preparata SilvaDeprex u patsiyentov s depressivnymi rasstroystvami v parallelnykh gruppakh [Evaluation of SilvaDeprex in patients with depressive disorders in parallel groups]. Latvijas ārsts, vol. 3, pp. 72-77.

10. Klinicheskiy protokol «Okazaniye meditsinskoy pomoshchi patsiyentam s psikhicheskimi i povedencheskimi rasstroystvami» ["Provision of medical care to patients with mental and behavioral disorders"]. Prilozheniye k prikazu MZ RB ot 31 dekabrya 2010 g. № 1387.

11. Essential Medicines and Health Products Information Portal A World Health. Organization resource. Available at: http://apps.who.int/medicinedocs/en/d/Js17534en/. 02.02.2018 (unpublished).

12. EMA Assessment Report on Hypericum perforatum L. herba - European Medicines Agency Monograph. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_ report/2010/01/WC500059144.pdf. 02.02.2018 (unpublished).

13. European Medicines Agency Monograph. Available at: http://www.ema.europa.eu/ema/index.jsp?curl= pages/medicines/landing/herbal_search.jsp&mid=WC0b01ac058001fa1d. 02.02.2018 (unpublished).

14. Treiber K., Singer A. (2005) Hyperforin activates nonselective cation channels (NSCCs). British Journal of Pharmacology, vol. 145, pp. 75-83.

15. Anghelescu I.G., Kohnen R., Szegedi A., Klement S., Kieser M. (2006) Comparison of hypericum extract WS 5570 and paroxetine in ongoing treatment after recovery from an episode of moderate to severe depression: results from a randomized multicenter study. Pharmacopsychiatry, vol. 39, no 6, pp. 213-219.

16. Behnke K., Jensen G.S., Granbanm P.I., Gruenwald J. (2002) Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression. Adv Ther, vol. 19, no 1, pp. 43-52.

17. Bjerkenstedt L., Edman G.V., Aiken R.G., Mannel M. (2005) Hypericum extract LI 160 and fluoxetine in mild to moderate depression: a randomized, placebo-controlled multi-center study in outpatients. Eur Arch Psychiatry Clin Neurosci, vol. 255, no 1, pp. 40-47.

18. Linde K., Berner M., Egger M (2005) Mulrow C. St John’s wort for depression. British Journal of Psychiatry,

19. vol. 186, pp. 99-107.

20. Barnes J., Anderson A., Phillipson J.D. (2001) St John’s Wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties. JPP, vоl. 53, pp. 583-600.

21. Kasper S., Anghelescu I.G., Szegedi A., Dienel A., Kieser M. (2006) Superior efficacy of St John’s wort extract WS 5570 compared to placebo in patients with major depression: a randomized, double-blind, placebo- controlled, multi-center trial. ВМС Medicine, vol. 4, pp. 14-27.

22. Kaufman J.H., Cannon-Smith T. (2007) Improved ejaculatory control and sexual satisfaction in pilot study of men taking Hypericum perforatum extract. Internet J Nutr Wellness, vol. 3. p. 2.

23. Wheatley D. (1999) Hypericum in seasonal affective disorder (SAD). Current medical research and opinion,

24. vol. 15, no 1, pp. 33-37.

25. ЕМА Assessment Report on Rhodiola rosea radix. Available at: http://www.ema.europa.eu/docs/en_GB/ document_library/Herbal_-_HMPC_assessment_report/ 2011/09/WC500112675.pdf. 02.02.2018.

26. Panossian A., Wikmcm G., Sairis J. Rosenroot (2010) Rhodiola rosea: traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine, vol. 17, pp. 481-493.

27. Van Diermen D., Mansion Bravo J., Reisi M., Corrupt P.A., Hostettmann K. (2009) Monoamine oxidase inhibition by Rhodiola rosea L. roots. Journal of Ethnopharmacology, vol. 122, pp. 397-401.

28. Darbinyan V., Aslanyan G., Amroyan E., Gabrielyan E., Malms from C, Panossian A. (2007) Clinical trial of Rhodiola rosea L. extract SITR-5 in the treatment of mild to moderate depression. Nord J Psychiatry, vol. 61, no 5, pp. 343-348.

29. Sheng Q.S., Wang Z.J., Zhang J., Zhang Y.G. (2013) Saliclroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats. Neuroreport, vol. 24, no 5, pp. 217-223.

30. Fintelmann V., Griienwcild J. (2007) Efficacy and tolerability of a Rhodiola roseci extract in adults with physical and cognitive deficiencies. Adv Ther, vol. 24, no 4, pp. 929-939.

31. List of references supporting the assessment of Valeriana officinalis L., radix and Valeriana officinalis L., aetheroleum. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/ Herbal_-_List_of_ references_supporting_the_assessment_report/2015/07/WC500190428.pdf. 02.02.2018.

32. ЕМА Assessment Report on Valeriana officinalis (L.), radix. Available at: http://www.ema.europa.eu/docs/ en_GB/document_library/Herbal_List_of_references_supporting_the_assessment_report/2015/07/ WC500190428.pdf. 02.02.2018.

33. Houghton Р.J. (1999) The scientific basis for the reputed activity of valerian. J Pharm Pharmacol, vol. 51, no 5, pp. 505-512.

34. Salter S., Brownie S. (2010) Treating primary insomnia. The efficacy of valerian and hops. Australian Family Physician, vol. 39, no 6, pp. 433-437.

35. Fernandez-San-Martin M., Masci-Font R., Palacios-Soler L, Sancho-Gomez P., Calbo-Caldentey C., Flores- Mateo G. (2010) Effectiveness of valerian on insomnia: a meta-analysis of randomized placebo-controlled trials. Sleep Med, vol. 11, no 6, pp. 505-511.

36. Kuang P.I., Sun S., Yang B., Xia Y., Feng W. (2009) New megastigmane sesquiterpene and indole alkaloid glucosides from the aerial parts of Bupleurum chinense DC. Fitoterapia, vol. 80, no 1, pp. 35-38.

37. Li X., Jia Y., Song A., Chen X., Bi K. (2005) Analysis of the essential oil from radix bupleuri using capillary gas chromatography, Yakugaku Zasshi, vol. 125, no 10, pp. 815-819.

38. Xie Y., Lu W., Cao S., Jiang X., Yin M., Tang W. (2006) Preparation of bupleurum nasal spray and evaluation on its safety and efficacy. Chem Pharm Bull, vol. 54, no 1, pp. 48-53.

39. Lee В.B., Yun I.P.Y., Shim I.S., Lee P.I.J., Hahm D.P.I. (2012) Bupleurum falcatum prevents depression and anxiety-like behaviors in rats exposed to repeated restraint stress. Journal of Microbiology and Biotechnology, vol. 22, no 3, pp. 422-430.

40. Shamloul R. (2010) Natural aphrodisiacs. J Sex Med, vol. 7, no 1, pp. 39-49.

41. Tang W., Hioki H., Наrada К., Kubo М., Fukuyama Y. (2008) Clerodane diterpenoids with NGF-potentiating activity from Ptychopetalum olacoides. J Nat Prod, vol. 71, no 10, pp. 1760-1763.

42. Tang W., Kubo M., Haradci K., Hioki H., Fukuyama Y. (2009) Novel NGF-potentiating diterpenoids from a Brazilian medicinal plant, Ptychopetalum olacoides. Bioorg Med Chem Lett, vol. 19, no 3, pp. 882-886.

43. Tang W., Harcida K., Kubo M., Hioki H., Fukuyama Y. (2011) Eight new clerodane diterpenoids from the bark of Ptychopetalum olacoides. Nat Prod Commun, vol. 6, no 3, pp. 327-332.

44. Figueiro P.L., Ilhci J., Pochmcmn I., Porciuncula L.O., Xavier L.L., Achaval P.L., Nunes S., Elisabetsky E. (2010) Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Muira puama). Phytomedicine, vol. 17, pp. 956-962.

45. Piato A.L, Detanico В.C., Line V.M., Herrmann A.P., Nunes D.S., Elisabetsky E. (2010) Anti-stress effects of the "tonic" Ptychopetalum olacoides. Phytomedicine, vol. 17, pp. 248-253.

46. Siqueira I.R., Cimarosti H., Fochesatto C., Nunes D.S., Salbego C., Elisabetsky E., Netto C.A. (2004) Neuroprotective effects of Ptychopetalum olacoides Bentham (Olacaceae) on oxygen and glucose deprivation induced damage in rat hippocampal slices. Life Sciences, vol. 75, pp. 1897-1906.

47. Murray М. (1994) Yohimbine vs Muira puama in the treatment of erectile dysfunction. The American Journal of Natural Medicine, vol. 1, no 3, p. 8.

48. Beck V., Rohr U., Jim A. (2005) Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy. J Steroid Biochem Mol Biol, vol. 94, no 5, pp. 499-518.


Для цитирования:


Вдовиченко В.П., Гончарук В.В., Борисенок О.А. СилваДепрекс: фармакологические особенности фитокомпозициидля поддержания нормального функционального состояния нервной системы. Рецепт. 2018;(5):565-571.

For citation:


Vdovichenko V..., Goncharuk V..., Borisenok O... SilvaDeprex: pharmacological features of phytocomposition for maintaining of normal functional state of nervous system. Recipe. 2018;(5):565-571. (In Russ.)

Просмотров: 18


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1993-4882 (Print)
ISSN 2414-2263 (Online)