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Омега-3 полиненасыщенные жирные кислоты – адъювантная защита от COVID-19

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Аннотация

В статье представлены данные о свойствах омега-3 полиненасыщенных жирных кислот (ПНЖК), об их участии в физиологических процессах организма при COVID-19. Рассмотрены возможные механизмы использования омега-3 ПНЖК при ковидной инфек

Об авторах

В. Г. Цапаев

Беларусь

Минск



Н. Л. Цапаева
Белорусский государственный медицинский университет
Беларусь

Минск



Список литературы

1. Martín-Acebes M.A., Vázquez-Calvo Á., Caridi F., Saiz J.-C.and Sobrino F. (2013) Lipid Involvement in Viral Infections: Present and Future Perspectives for the Design of Antiviral Strategies. licensee InTech., 13, pp. 291–322.

2. Saedisomeolia A., Wood L.G., Garg M.L., Gibson P.G., Wark P.A. (2009) Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells. Br. J. Nutr., vol. 101 , pp. 533–40. Crossref.

3. Kohn A., Gitelman J., Inbar M. (1980) Interaction of Polyunsaturated Fatty Acids with Animal Cells and Enveloped Viruses. Antimicrobial agents and chemotherapy, no 18 (6), pp. 962–968.

4. Kang K.W., Kim S., Cho Y.B., Ryu S.R., Seo Y.J., Lee S.M. (2019) Endogenous n-3 polyunsaturated fatty acids are beneficial to dampen CD8+ T cellmediated inflammatory response upon the viral infection in mice. Int J Mol Sci., vol. 20, p. 4510.

5. Schwab J.M., Chiang N., Arita M., Serhan C.N. (2007) Nature, vol. 447, p. 869.

6. Charles N. Serhan, Nicos A. Petasis (2011) Resolvins and Protectins in Inflammation-Resolution. Chem Rev., vol. 111, pp. 5922–5943.

7. Hinojosa C.A., Gonzalez-Juarbe C.A., Rahman M.M., Fernandes G., Orihuela C.J., Restrepo M.I. (2020) Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia. Microb. Pathog., vol. 141, p. 103979.

8. Miljanovic B., Trivedi K.A., Dana M.R., Gilbard J.P., Buring J.E., Schaumberg D.A. (2005) Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am. J. Clin. Nutr., vol. 82, pp. 887–93.

9. Calder P.C., Adolph M., Deutz N.E., Grau T., Innes J.K., Klek S., Lev S., Mayer K., Michael-Titus A.T., Pradelli L., Puder M., Vlaardingerbroek H., Singer P. (2018) Lipids in the intensive care unit: recommendations from the ESPEN expert group. Clin. Nutr., vol. 37, pp. 1–18.

10. Chen H., Wang S., Zhao Y. (2018) Correlation analysis of omega-3 fatty acids and mortality of sepsis and sepsis-induced ARDS in adults: data from previous randomized controlled trials. Nutr J., vol. 17: 57, pp. 1–14.

11. Messina G., Polito R., Monda V., Cipolloni L., Di Nunno N., Di Mizio G., Murabito P., Carotenuto M., Messina A., Pisanelli D., Valenzano A., Cibelli G., Scarinci A., Monda M., Sessa F. (2020) Functional role of dietary intervention to improve the outcome of COVID-19: a hypothesis of work. Int. J. Mol Sci., vol. 21, p. 3104.

12. Doaei S., Gholami S., Rastgoo S. (2020) The effect of omega-3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID-19: a randomized clinical trial. J. Transl. Med., vol. 19, pp. 2–9.

13. Korner A., Schlegel M., Theurer J., Frohnmeyer H., Adolph M., Heijink M., Mirakaj V. (2018) Resolution of inflammation and sepsis survival are improved by dietary Omega-3 fatty acids. Cell Death and Differentiation, vol. 25, pp. 421–431.

14. Darwesh A.M., Bassiouni W., Sosnowski D.K. (2021) Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID- 19-associated cardiovascular complications? Pharmacology & Therapeutics, vol. 219, pp. 1–27.

15. Thibault R., Seguin P., Tamion F. (2020) Nutrition of the COVID-19 patient in the intensivecare unit (ICU): apractical guidance. Crit.Care, vol. 24, p. 447.

16. Tintle N.L., Myers M. (2021) Blood omega-3 fatty acids and death from COVID-19: A pilot study. Arash Asher, Prostaglandins Leucot Essent Fatty Acids, vol. 166.

17. Liu S.Y., Aliyari R., Chikere K., Li G., Marsden M.D., Smith J.K., Pernet O., Guo H., Nusbaum R., Zack J.A. (2013) Interferon-inducible cholesterol-25- hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity, vol. 38, pp. 92–105.

18. Eslamloo K., Xue X., Hall J.R., Smith N.C., Caballero-Solares A., Parrish C.C., Taylor R.G., Rise M.L. (2017) Transcriptome profiling of antiviral immune and dietary fatty acid dependent responses of Atlantic salmon macrophage-like cells. BMC Genomics, vol. 18, p. 706.

19. Goc A., Niedzwieck A., Rath M. (2021) Polyunsaturated ω-3 fatty acids inhibit ACE2-controlled SARS-CoV-2 binding and cellular entry. Scientific Reports, vol. 11, p. 5207.


Для цитирования:


Цапаев В.Г., Цапаева Н.Л. Омега-3 полиненасыщенные жирные кислоты – адъювантная защита от COVID-19. Рецепт. 2021;(5):634-645.

For citation:


Tsapaev V., Tsapaeva N. Omega-3 Polyunsaturated Fatty Acids as Adjuvant Protection against COVID-19. Recipe. 2021;(5):634-645. (In Russ.)

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ISSN 1993-4882 (Print)
ISSN 2414-2263 (Online)