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Роль витамина D при артериальной гипертензии высокого кардиоваскулярного риска

https://doi.org/10.34883/PI.2020.2.2.040

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Аннотация

Представлен обзор литературных данных по влиянию витамина D на состояние пациентов с артериальной гипертензией, сочетающейся с ожирением и дислипидемией. Описаны потенциальные механизмы, благодаря которым витамин D может влиять на сосудистую стенку, функцию эндотелия, уровень холестерина и липопротеинов низкой плотности, толерантность к глюкозе, уровень инсулина и чувствительность к нему, количество рецепторов к инсулину, участвовать в процессах воспаления. Представлены результаты исследований, описывающих эффекты приема препаратов витамина D при сердечно-сосудистых заболеваниях, сахарном диабете. Описано влияние витамина D на подавление кальцификации сосудов, ингибирование пролиферации гладкомышечных клеток сосудов, регуляцию уровня провоспалительных цитокинов и ренин-ангиотензин-альдостероновой системы. Выполненный нами анализ литературных данных свидетельствует о необходимости продолжения исследований с оценкой эффективности коррекции сниженного уровня витамина D в крови у пациентов с АГ, протекающей в сочетании с ожирением, дислипидемией.

Об авторах

К. в Гончар
Гродненский государственный медицинский университет
Беларусь


Л. В. Якубова
Гродненский государственный медицинский университет
Беларусь


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Для цитирования:


Гончар К.в., Якубова Л.В. Роль витамина D при артериальной гипертензии высокого кардиоваскулярного риска. Рецепт. 2020;(2-3):337-341. https://doi.org/10.34883/PI.2020.2.2.040

For citation:


Hanchar .K., Yakubava .L. The Role of Vitamin D in High Cardiovascular Risk Hypertension. Recipe. 2020;(2-3):337-341. (In Russ.) https://doi.org/10.34883/PI.2020.2.2.040

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